Charlie Hindmarch

2017

Gökçe Yıldırım-Buharalıogu, Mark Bond, Graciela B. Sala-Newby, Charles C. T. Hindmarch and Andrew C. Newby (2017) Regulation of Epigenetic Modifiers, Including KDM6B, by Interferon-γ and Interleukin-4 in Human Macrophages Front Immunol 8:92

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Hoay Yan Cheah, Olivera Šarenac, Juan J. Arroyo, Marko Vasić, Maja Lozić, Sofija Glumac, Charlie Hindmarch, David Murphy, Lik Voon Kiew , Hong Boon Lee, Marίa J.Vicent, Lip Yong Chung d, Nina Japundžić-Žigon (2017) Hemodynamic effects of HPMA copolymer based doxorubicin conjugate: a randomized controlled and comparative spectral study in conscious rats. Nanotox (2):210-222

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Jack E. Teasdale, Georgina G. J. Hazell, Alasdair M. G. Peachey, Graciela B. Sala-Newby, Charles C. T. Hindmarch, Tristan R. McKay, Mark Bond, Andrew C. Newby and Stephen J. White (2017). Cigarette smoke extract profoundly suppresses TNFα-mediated proinflammatory gene expression through upregulation of ATF3 in human coronary artery endothelial cells. Sci Reports7:39945

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2016

Maja Lozić, Tatjana Tasić, Andrew Martin, Michael Greenwood, Olivera Šarenac, Charles Hindmarch, Julian Paton, David Murphy, Nina Japundžić-Žigon Over-expression of V1a receptors in PVN desensitizes baroreflex and increases cardiovascular variability during stress Pharmacol res 114:185-195

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Lulu Jiang, Charles Hindmarch, Mark Rogers, Christy Waterfall, Jane Coghill, Peter W. Mathieson, Gavin I Welsh (2017) RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways. Sci Reports 6:35671

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Hindmarch C & Ferguson AV (2016) Physiological roles for the subfornical organ: a dynamic transcriptome shaped by autonomic state. J Physiol.  594(6): 1581-9

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2015 

Hindmarch C*, Johnson K*, Salinas Y, Shi Y, Greenwood M, Ziau H, Murphy D and Gainer H (2015) A RNA-Seq Analysis of the Rat Supraoptic Nucleus Transcriptome: Effects of Salt Loading on Gene Expression.– PlosOne. 10(4) e0124523 *Joint first author

 

Konopacka A, Qiu J, Yao S, Greenwood M, Greenwood M, Lancaster T, Inoue W, Mecawi A, Vechiato F, Lima J, Coletti R, Hoe S, Martin A, Lee J, Joseph M, Hindmarch C, Paton J, Antunes-Rodrigues J, Bains J, Murphy D (2015) Osmoregulation requires brain expression of the renal Na-K-2Cl co-transporter NKCC2 – J Neurosci. 2015 Apr 1;35(13):5144-55

 

Greenwood M, Mecawi A, Johnson K, Hoe S, Mustafa R, Gainer H, Murphy D* & Hindmarch C* (2015) The behavioural, hormonal and transcriptomic response to water restriction and salt loading in the rat – American Journal of Physiology – Integrative and Comparative Physiology – Am J Physiol Regul Integr Comp Physiol. 2015 Apr 1;308(7):R559-68 * Joint Senior Author

 

2014

Qiu J, Kleineidam A, Gouraud S, Yao S, Greenwood M, Hoe S, Hindmarch C, Murphy D (2014) The use of protein-DNA arrays, chromatin immunoprecipitation arrays, and transcriptome arrays to describe transcriptional circuits in the dehydrated rat hypothalamus – In press, Endocrinology.

 

Smith P, Hindmarch C, Murphy D, Ferguson A (2014) AT1 receptor blockade alters nutritional and biometric development in AT1 receptor blockade alters nutritional and biometric development in obesity-resistant and obesity-prone rats submitted to a high fat diet – In press, Frontiers in Psychology – Eating Behaviour

 

Lozić-Đurić M, Greenwood M, Šarenac O, Martin A, Hindmarch C, Tasić T, Paton J, Murphy D, Japundžić-Žigon N (2014) Over Exrression of Oxytocin receptors in the hypothalamic PVN increases BRS and buffers BP variability in conscious rats. British J. Pharmacol – in press

 

Kimura TE, Duggirala A, Hindmarch C, Hewer RC, Cui MZ, Newby AC & Bond M (2014). Protein kinase A and EPAC synergistically inhibit Egr1 expression and proliferation in vascular smooth muscle cells. . J Mol and Cell Card 2014;72:9-19.

 

2013

 

Hindmarch C, Franses P, Goodwin B & Murphy D (2013). Whole transcriptome organisation in the dehydrated supraoptic nucleus. Braz J Med Biol Res 46, 1000-1006.

 

Li AH, Hindmarch C, Nattie EE, Paton JFR. Treating hypertension by targeting orexin receptors: potential effects on the sleep-related blood pressure dipping profile Reply. J Physiol-London. 2013;591(23):6117-.

 

Li AH, Hindmarch C, Nattie EE, Paton JFR. Antagonism of orexin receptors significantly lowers blood pressure in spontaneously hypertensive rats. J Physiol-London. 2013;591(17):4237-48.

 

Waki H, Hendy EB, Hindmarch C, Gouraud S, Toward M, Kasparov S, Murphy D & Paton JF (2013). Excessive leukotriene B4 in nucleus tractus solitarii is prohypertensive in spontaneously hypertensive rats. Hypertension 61, 194-201.

 

2012

 

Murphy D, Konopacka A, Hindmarch C, Paton JF, Sweedler JV, Gillette MU, Ueta Y, Grinevich V, Lozic M & Japundzic-Zigon N (2012). The hypothalamic-neurohypophyseal system: from genome to physiology. J Neuroendocrinol 24, 539-553.

 

Hindmarch P, Hindmarch C, Murphy D & Wright J (2012). Use of intravenous fluids for the treatment of patients intoxicated with ethanol (alcohol); a scientific based practice, but with no clinical guidelines. Eur J. Emerg Med 19, 410.

 

Hazell GG, Hindmarch C, Pope GR, Roper JA, Lightman SL, Murphy D, O'Carroll AM & Lolait SJ (2012). G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis. Front Neuroendocrinol 33, 45-66.

 

2011

 

Hindmarch C, Qiu J, Yao ST, Tasker JG & Murphy D (2011). Transcriptomic analysis of the osmotic and reproductive remodeling of the female rat supraoptic nucleus. Endocrinology 152, 3483-3491. Joint First Author

 

Colombari DS, Colombari E, Freiria-Oliveira AH, Antunes VR, Yao ST, Hindmarch C, Ferguson AV, Fry M, Murphy D & Paton JF (2011). Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration. J Physiol 589, 4457-4471.

 

Hindmarch C, Fry M, Smith PM, Yao ST, Hazell GG, Lolait SJ, Paton JF, Ferguson AV & Murphy D (2011). The transcriptome of the medullary area postrema: the thirsty rat, the hungry rat and the hypertensive rat. Exp Physiol 96, 495-504. Experimental Physiology Early Career Author Prize

 

Hindmarch C, Stewart L, Qiu J, Tung YC, Yeo GS & Murphy D (2011). Hypothalamic transcriptome plasticity in two rodent species reveals divergent differential gene expression but conserved pathways. J Neuroendocrinol 23, 177-185. Joint First Author

 

2006- 2010

 

Hindmarch C & Murphy D (2010). The transcriptome and the hypothalamo-neurohypophyseal system. Endocr Dev 17, 1-10.

 

Hindmarch C, Fry M, Yao ST, Smith PM, Murphy D & Ferguson AV (2008). Microarray analysis of the transcriptome of the subfornical organ in the rat: regulation by fluid and food deprivation. Am J Physiol Regul Integr Comp Physiol 295, R1914-1920.

 

Hindmarch C, Yao S, Hesketh S, Jessop D, Harbuz M, Paton J & Murphy D (2007). The transcriptome of the rat hypothalamic-neurohypophyseal system is highly strain-dependent. J Neuroendocrinol 19, 1009-1012.

 

Qiu J, Yao S, Hindmarch C, Antunes V, Paton J & Murphy D (2007). Transcription factor expression in the hypothalamo-neurohypophyseal system of the dehydrated rat: upregulation of gonadotrophin inducible transcription factor 1 mRNA is mediated by cAMP-dependent protein kinase A. J Neurosci 27, 2196-2203.

 

Hindmarch C, Yao S, Beighton G, Paton J & Murphy D (2006). A comprehensive description of the transcriptome of the hypothalamoneurohypophyseal system in euhydrated and dehydrated rats. Proc Natl Acad Sci U S A 103, 1609-1614. See also: Maghnie MS, A. Loche, S. (2006). Pituitary - Mechanism of the Year - Hindmarch et al. Karger, Basel.

 

Ghorbel MT, Sharman G, Hindmarch C, Becker KG, Barrett T & Murphy D (2006). Microarray screening of suppression subtractive hybridization-PCR cDNA libraries identifies novel RNAs regulated by dehydration in the rat supraoptic nucleus. Physiol Genomics 24, 163-172.